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Members include individuals who suffered severe side effects with Accutane and their families. We are in contact with similar groups from UK, USA France, Norway and other countries. Accutane is an analog of Vitamin A. The Journal of the American Academy of Dermatology 18, 543-552, 1988. Isotretinoin and depression: care is needed.

Acne has been proposed to be a cause of depression. Table 1 Worldwide psychiatric ADR reports Number of people prescribed Accutane worldwide – 6 million Number of people prescribed the other 5 Acne meds. Data for Roaccutane cut-off date July 1999 Earliest Reaction date February 15 1993 Medication No. France -3rd March 1997 Label warnings featuring various behavioural and psychiatric disorders was introduced in France and the warning featured suicide as a possible side effect.

Canadian Label Warning, May 2000 No reference to depression, psychiatric disorders or suicide. Following implementation of suicide warnings on Accutane packets Roche placed advertisements in Irish Medical Journals featuring letters from Dr. Dose response study of 13-cis-retinoic acid in acne vulgaris Jones, D. Accutane interacts with the Central Nervous System and other systems in the body. Accutane should only be used for severe recalcitrant cystic acne as a treatment of last resort.

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